Ankylosing Spondylitis
What is it and how is it treated by the spine specialists at Tailored Medical Management?
What Is Ankylosing Spondylitis?
Causes
There are no known causes other than genetic factors. It has been observed, through research, that the HLA-B27 gene significantly increases the chances of developing this condition. Studies show that 9 out of 10 individuals with Ankylosing Spondylitis carry a gene known as the human leukocyte antigen (HLA) B27.
Symptoms
The initial symptoms and signs of Ankylosing Spondylitis include stiffness and pain in the hips and lower back, particularly in the morning and after inactivity. Fatigue (or tiredness), inflammation and swelling in the knees (and ribs) are also common symptoms. As time passes, these symptoms can improve, worsen, or occur only at irregular intervals.
Generally, the areas affected include:
- The cartilage between ribs and breastbone
- Shoulder joints
- The joint between pelvis and base of the spine
- Hip
- The vertebrae in lower back
- The areas where ligaments and tendons attach to the bones
Video Education

Personalized Care.
Dr. Senatus & Dr. Karim employ a personalized patient-centered approach that prioritizes optimum functional outcome and well-being. Each consultation begins with a comprehensive evaluation by our team designed to create an individualized evidence based treatment plan which includes the patient, family, and collaborating providers.
Start Here. We'll Call You.

Ivy League Trained
Our specialists have trained at the worlds top medical institutions including Harvard, Yale, Columbia University Medical Center and The Prestigious Cleveland Clinic.

Upper East Side
We are located at 800A 5th Ave, Suite 402, New York, NY 10065 in the Upper East Side section of Manhattan directly across from Central Park.
You will be welcomed into our boutique office where your time is of premium value. That means little to no waiting and extensive consultation with Dr. Senatus to understand what is causing your pain and what steps can be taken to return you to a functional pain-free lifestyle.
(646) 960-8545